3D VARIABILITY ANALYSIS REVEALS A HIDDEN CONFORMATIONAL CHANGE CONTROLLING AMMONIA TRANSPORT IN HUMAN ASPARAGINE SYNTHETASE

3D variability analysis reveals a hidden conformational change controlling ammonia transport in human asparagine synthetase

Abstract Advances in X-ray crystallography and cryogenic electron microscopy (cryo-EM) offer the promise of elucidating functionally relevant conformational changes that are not easily studied by other VITAMIN A DROPS biophysical methods.Here we show that 3D variability analysis (3DVA) of the cryo-EM map for wild-type (WT) human asparagine syntheta

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Enhancing Internet of Things security using performance gradient boosting for network intrusion detection systems

The rise of the Internet of things (IoT) changes inter-device communication to increase efficacy and livability conditions in all sectors.However, it is proportion of security vulnerabilities making IoT networks prime targets for sophisticated cyber threats.The deployment of solution methods is needed to embark on new grounds in exploring IoT cyber

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Challenges Facing Practical Theology

Practical theology can be considered as a kind of practical and functional expansion of theological teachings or something derived from theology in human life.The present article, considering the general meaning of theology, addresses some of the challenges facing practical theology.The first challenge: human expectation of religion.It is according

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